實驗室研究成果

臺大基因體醫學研究中心 遺傳流行病學核心實驗室

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Journal Papers

利用本核心實驗室之部份檢體、分析技術、或實驗設備所發表之相關研究成果

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研討會論文
Seminar reports & posters

專書/專書章節
Books & Book sections

  • Genetic Epidemiology Related

    1. Wang S-H, Hsiao P-C, Yeh L-L, Liu C-M, Liu C-C, Hwang T-J, Hsieh M-H, Chien Y-L, Lin Y-T, Chandler SD, Faraone SV, Laird N, Neale B, McCarroll SA, Glatt SJ, Tsuang MT, Hwu H-G, Chen WJ (in press): Polygenic risk for schizophrenia and neurocognitive performance in patients with schizophrenia. Genes, Brain and Behavior. [SCI]

    2. Woolston AL, Hsiao P-C, Kuo P-H, Wang S-H, Lien Y-J, Liu C-M, Hwu H-G, Lu T-P, Chuang E, Chang L-C, Chen C-H, Wu J-Y, Tsuang MT, Chen W-J (2017): Genetic loci associated with an earlier age at onset in multiplex schizophrenia. Scientific Reports 7: 6486. [SCI]

    3. Lin JH, Lee WC (2016): Complementary log regression for sufficient cause modeling of epidemiologic data. Scientific Reports 6: 39023. [SCI]

    4. Chen YC, Hsiao CJ, Jung CC, Hu HH, Chen JH, Lee WC, Chiou JM, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen CJ, Yang HI (2016): Performance Metrics for Selecting Genetic Polymorphisms in Late-onset Alzheimer’s Disease. Scientific Reports 6: 36155. [SCI]

    5. Tsuang H-C, Chen WJ, Kuo S-Y, Hsiao P-C (2016): Handedness and schizotypy: the potential effect of changing writing-hand. Psychiatry Research. 242: 198-203. [SCI, SSCI]

    6. Kao CF, Chen HW, Chen HC, Yang JH, Huang MC, Chiu YH, Lin SK, Lee YC, Liu CM, Chuang LC, Chen CH, Wu JY, Lu RB, Kuo PH (2016): Identification of susceptible loci and enriched pathways for bipolar II disorder using genome-wide association studies. International Journal of Neuropsychopharmacology 19(12): pyw064. [SCI]

    7. Yang YH, Lin WY, Lee WC (2016): A fuzzy permutation method for false discovery rate control. Scientific Reports 6: 28507. [SCI]

    8. Lee WC (2016): Optimal trend tests for genetic association studies of heterogeneous diseases. Scientific Reports 6: 27821. [SCI]

    9. Weng PH, Chen JH, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC (2016): CHRNA7 Polymorphisms and Dementia Risk: Interactions with Apolipoprotein ε4 and Cigarette Smoking. Scientific Reports 6: 27231. [SCI]

    10. Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Bui ET, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dantas CR, Dayer A, Étain B, Falkai P, Forstner AJ, Frisén L, Fullerton JM, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Ösby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm T, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt S, Wright A, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus EZ, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, Rietschel M, McMahon FJ, Schulze TG. (2016): Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. The Lancet 387(10023), 1085-1093. [SCI]

    11. Liu, Y.-L., Wang, S.-C., Hwu, H.-G., Fann, C. S.-J., Yang, U.-C., Yang, W.-C., Hsu, P.-C., Chang, C. C., Wen, C.-C., Tsai-Wu, J.-J., Hwang, T.-J., Hsieh, M. H., Liu, C.-C., Chien, Y.-L., Fang, C.-P., Faraone, S. V., Tsuang, M. T., Chen, W. J. & Liu, C.-M. (2016): Haplotypes of the D-amino acid oxidase gene are significantly associated with schizophrenia and its neurocognitive deficits. PLoS ONE 11(3): e0150435. [SCI]

    12. Lai C.-Y., Scarr E., Udawela M., Everall I., Chen W.J., Dean B (2016): Biomarkers in schizophrenia: A focus on blood based diagnostics and theranostics. World Journal of Psychiatry 6: 102-117.

    13. Su YS, Lee WC (2016): False appearance of gene-environment interactions in genetic association studies. Medicine 95(9): e2743. [SCI]

    14. Chen JH, Hsieh CJ, Huang YL, Chen YC, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM (2016): Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer’s disease and vascular dementia. Journal of the Formosan Medical Association 115: 38-44. [SCI]

    15. Lai, C.-Y., Lee, S.-Y., Scarr, E., Yu, Y.-H., Lin, Y.-T., Liu, C.-M., Hwang, T.-J., Hsieh, M. H., Liu, C.-C., Chien, Y.-L., Udawela, M., Gibbons, A. S., Everall, I. P., Hwu, H.-G., Dean, B. & Chen, W. J. (2016): Aberrant expression of microRNAs as biomarker for schizophrenia: From acute state to partial remission, and from peripheral blood to cortical tissue. Translational Psychiatry 6: e717. [SCI]

    16. Lee WC, Wu YC (2016): Characterizing decision-analysis performances of risk prediction models using ADAPT curves. Medicine 95(2): e2477. [SCI]

    17. Dean, B., Thomas, N., Lai, C.-Y., Chen, W. J. & Scarr, E. (2015): Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia. Schizophrenia Research 169: 83-88. [SCI,SSCI]

    18. Yang SY, Weng PH, Chen JH, Chiou JM, Lew-Ting CY, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC (2015): Leisure Activities, Apolipoprotein E e4 Status, and the Risk of Dementia. Journal of the Formosan Medical Association 114(12): 1216–1224. [SCI]

    19. Hwang, T.-J., Lo, W.-M., Chan, H.-Y., Lin, C.-F., Hsieh, M. H., Liu, C.-C., Liu, C.-M., Hwu, H.-G., Kuo, C.-H. & Chen, W. J. (2015): Fast versus slow strategy of switching patients with schizophrenia to aripiprazole from other antipsychotics. Journal of Clinical Psychopharmacology 35: 635-644. [SCI]

    20. Chen S-C, Chu N-H, Hwu H-G, Chen Wei J. (2015): Trajectory classes of violent behavior and their relationship to lipid levels in schizophrenia inpatients. Journal of Psychiatric Research 66-67: 105-111. [SCI, SSCI]

    21. Hsieh CJ, Weng PH, Chen JH, Chen TF, Sun Y, Weng LL, Yiph PK, Chui YM, Chen YC (2015): Sequence variants of the aging gene CISD2 and the risk of Alzheimer’s disease. Journal of the Formosan Medical Association 114(7): 627–632. [SCI]

    22. Rees, E., Kirov, G., Walters, J. T., Richards, A. L., Howrigan, D., Kavanagh, D. H., Pocklington, A. J., Fromer, M., Ruderfer, D. M., Georgieva, L., Carrera, N., Gormley, P., Palta, P., Williams, H., Dwyer, S., Johnson, J. S., Roussos, P., Barker, D. D., Banks, E., Milanova, V., Rose, S. A., Chambert, K., Mahajan, M., Scolnick, E. M., Moran, J. L., Tsuang, M. T., Glatt, S. J., Chen, W. J., Hwu, H. G., The Taiwanese Trios Exome Sequencing, C., Neale, B. M., Palotie, A., Sklar, P., Purcell, S. M., McCarroll, S. A., Holmans, P., Owen, M. J. & O'Donovan, M. C. (2015): Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia. Translational Psychiatry 5: e607. [SCI]

    23. Wang S-H, Liu C-M, Hwu H-G, Hsiao CK, Chen, WJ (2015): Association of older paternal age with earlier onset among co-Affected schizophrenia sib-pairs. Psychological Medicine 45(10): 2205-2213. [SCI, SSCI]

    24. Lien Y-J, Chen WJ, Hsiao P-C, Tsuang H-C (2015): Estimation of heritability for varied indexes of handedness. Laterality: Asymmetries of Body, Brain and Cognition 20: 469-482. [SSCI]

    25. Lin AS, Chang SS, Lin SH, Peng YC, Hwu HG, Chen WJ (2015): Minor physical anomalies and craniofacial measures in patients with treatment-resistant schizophrenia. Psychological Medicine 45(9): 1839-1850. [SCI, SSCI]

    26. Chen H-H, Tseng YJ, Wang S-Y, Tsai Y-S, Chang C-S, Kuo T-C , Yao W-J, Shieh C-C, Wu C-H, and Kuo P-H (2015): The metabolome profiling and pathway analysis in metabolic healthy and abnormal obesity. International Journal of Obesity 39: 1241–1248. [SCI]

    27. Wu Y-C, Lin Y-C, Yu H-L, Chen J-H, Chen T-F, Sun Y, Wen L-L, Yip P-K, Chu Y-M, Chen Y-C (2015): Association between air pollutants and dementia risk in elderly. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 1(2): 220-228.

    28. Wang L-Y, Lee W-C (2015): One-step extrapolation of the prediction performance of a gene signature derived from a small study. BMJ Open 5: e007170. [SCI]

    29. Lin JH, Lee WC (2015): Testing for mechanistic interactions in long-term follow-up studies. PLoS ONE 10(3): e0121638. [SCI]

    30. Lin HJ, Chen ST, Wu HY, Hsu HC, Chen MF, Lee YT, Wu KY, Chien KL (2015): Urinary biomarkers of oxidative and nitrosative stress and the risk for incident stroke: A nested case-control study from a community-based cohort. International Journal of Cardiology 183; 214-220. [SCI]

    31. Yang TK, Hsiao PJ, Yang HJ, Liao CH, Chiang HS, KL Chien (2015): Body mass index and age are predictors for symptom improvement after high-power laser vaporization for benign prostatic hyperplasia. Journal of the Formosan Medical Association 114(3): 268-273. [SCI]

    32. Tzeng IS, Lee WC (2015): Forecasting hepatocellular carcinoma mortality in Taiwan using an age-period-cohort model. Asia-Pacific Journal of Public Health 27(2): NP65-NP73. [SCI]

    33. Ting, T.-T., Huang, S.-Y., Chen, K.-H., Tseng, C.-I., Lin, K.-M., Chen, C.-Y., Chen, W.J. (2015): Effects of genetic variants of ADH1B and ALDH2 and social network on continued alcohol drinking among young adolescents in Taiwan. Drug and Alcohol Dependence 147: 38-45. [SCI]

    34. Liu PY, Lin LY, Lin HJ, Hsia CH, Hung YR, Yeh HI, Wu TC, Chen JY, Wen MS, Chien KL, Chen JW (2014): Pitavastatin and Atorvastatin Double-blind Randomized Comparative Study Among High-risk Patients, Including those with Type 2 Diabetes Mellitus, in Taiwan (PAPAGO-T study). PLoS ONE 9(11): e114175. [SCI]

    35. Hu GC, Chien KL, Su TC, Hsu HC, Hsieh SF, Lee YT (2014): Occupational versus Leisure-Time Physical Activity in Reducing Cardiovascular Risks and Mortality among Ethnic Chinese Adults in Taiwan. Asia-Pacific Journal of Public Health 26(6): 604-613. [SCI]

    36. Kao CF, Chuang LC, Kuo PH (2014): Risk and Information Evaluation of Priortized Genes for Complex Traits: Application to Bipolar Disorder. American Journal of Medical Genetics Part B 165(7): 596-606. [SCI]

    37. Wu Y-C, Leng C-H, Hsieh W-S, Hsu C-H, Chen WJ, Gau SS-F, Chiu N-C, Yang M-C, Fang L-J, Hsu H-C, Yu Y-T, Wu Y-T, Chen L-C, Jeng S-F (2014): A randomized controlled trial of clinic-based and home-based interventions in comparison with usual care for preterm infants: Effects and mediators. Research in Developmental Disabilities 35: 2384-2393. [SSCI]

    38. Lai C-Y, Wu Y-T, Yu S-L, Yu Y-H, Lee S-Y, Liu C-M, Hsieh W-S, Hwu H-G, Chen P-C, Jeng S-F, Chen WJ* (2014): Modulated expression of human peripheral blood microRNAs from infancy to adulthood and its role in aging. Aging Cell 13: 679-689. [SCI]

    39. Hu GC, Hsu CY, Yu HK, Chen JP, Chang YJ, Chien KL (2014): Association between the volume of inpatient rehabilitation therapy and the risk of all-cause and cardiovascular mortality in patients with ischemic stroke. Archives of Physical Medicine and Rehabilitation 95(2): 269-275. [SCI]

    40. Weng PH, Chen JH, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC (2013): CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer’s Disease. PLoS ONE 8(12): e84059. [SCI]

    41. Liu SC, Chien KL, Wang CH, Chen WC, Leung CH (2013): Efficacy and safety of adding pioglitazone or sitagliptin to patients with type 2 diabetes insufficiently controlled with metformin and a sulfonylurea. Endocrine practice 19(6): 980-988. [SCI]

    42. Tu YK, D'Aiuto F, Lin HJ, Chen YW, Chien KL (2013): Relationship between metabolic syndrome and diagnoses of periodontal diseases among participants in a large Taiwanese cohort. Journal of Clinical Periodontology 40(11): 994-1000. [SCI]

    43. Liao SF, Lee WC (2013): Sufficient cause modeling with matched data using SAS. Epidemiology 24(6): 936-937. (letter). [SCI]

    44. Lin JC, Lee WC (2013): Hazard ratio bias in cohort studies. Epidemiology 24(5): 777-778. (letter). [SCI]

    45. Lee WC (2013): Sample size calculations for additive interactions. Epidemiology 24(5): 774-775. (letter). [SCI]

    46. Lee WC (2013): Testing synergisms in a no-redundancy sufficient cause rate model. Epidemiology 24(1): 174-175. (letter). [SCI]

    47. Wu HY, Huang JW, Lin HJ, Liao WC, Peng YS, Hung KY, Wu KD, Tu YK, Chien KL (2013): Comparative Effectiveness of Various Renin-angiotensin System Blockers and Other Antihypertensive Drugs in Diabetic Patients: A Systematic Review and Bayesian Network Meta-analysis. British Medical Journal 347: f6008. [SCI]

    48. Liao WC, Chien KL, Lin YL, Wu MS, Lin JT, Wang HP, Tu YK (2013): Adjuvant Therapies for Resected Pancreatic Adenocarcinoma: A Systematic Review and Network Meta-analysis. The Lancet Oncology 14(11): 1095-1103. [SCI]

    49. Lip GYH, Lin HJ, Hsu HC, Su TC, Chen MF, Lee YT, Chien KL (2013): Comparative assessment of the HAS-BLED score with other published bleeding risk scoring schemes, for intracranial haemorrhage risk in a non-atrial fibrillation population: the Chin-Shan Community Cohort Study. International Journal of Cardiology 168(3): 1832-1836. [SCI]

    50. Lai TS, Wang CY, Pan SC, Huang TM, Lin MC, Lai CF, Wu CH, Chien KL (2013): Risk of developing severe sepsis after acute kidney injury: a population-based cohort study. Critical Care 17: R231. [SCI]

    51. Chen WJ (2013): Taiwan Schizophrenia Linkage Study: Lessons learned from endophenotype-based genome-wide linkage scans and perspective. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 162: 636-647. [SCI]

    52. Lin CY, Lee HL, Chen YC, Lien GW, Lin LY, Wen LL, Liao CC, Chien KL, Sung FC, Chen PC, Su TC (2013): Positive association between urinary levels of 8-hydroxydeoxyguanosine and the acrylamide metabolite n-acetyl-s-(propionamide)-cysteine in adolescents and young adults. Journal of Hazardous Materials 261: 372-377. [SCI]

    53. Hsieh RL, Hsueh YM, Huang HY, Lin MI, Lee WC (2013): The correlation of health of preschool Taiwanese children with developmental delay. Hong Kong Journal of Paediatrics 18: 159-166. [SCI]

    54. Fang CC, Chen WJ, Peng CL, Chen PC, Chien KL, Tsai TJ, Lee YT (2013): Renovascular disease in Taiwan: A long-term nationwide population study. International Journal of Cardiology 168(1): 541-542. [SCI]

    55. Chien KL, Lin HJ, Hsu HC, Chen PC, Su TC, Chen MF, Lee YT (2013): Comparison of Predictive Performance of Various Fatty Acids for the Risk of Cardiovascular Disease Events and All-cause Deaths in a Community-based Cohort. Atherosclerosis 230(1): 140-147. [SCI]

    56. Wang S-H, Chen WJ, Tsia Y-C, Huang Y-H, Hwu H-G, Hsiao CK (in press): A stochastic inference of de novo CNV detection and association test in multiplex schizophrenia families. Frontiers in Genetics 4: 185. [SCI]

    57. Wu YT, Chen WJ, Hsieh WC, Tsao PN, Yu SL, Lai CY, Lee WC, and Jeng SF (2013): MicroRNA expression aberration associated with bronchopulmonary dysplasia in preterm infants: a preliminary study. Respiratory Care 58: 1527-1535. [SCI]

    58. Hsieh RL, Wang LY, Lee WC (2013): Correlation between the incidence and severity of Bell’s palsy and seasonal variations in Taiwan. International Journal of Neuroscience123(7): 459-464. [SCI]

    59. Huang CJ, Wu CF, Lan CY, Sung FY, Lin CL, Liu CJ, Liu HF, Yu MW (2013): Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression.PLoS ONE 8: e70169. [SCI]

    60. Tsuang H-C, Chen W-J, Kuo S-Y, Hsiao P-C (2013): The cross-cultural nature of the relationship between schizotypy and mixed-handedness. Laterality: Asymmetries of Body, Brain and Cognition 8: 476-490. [SSCI]

    61. Lee WC (2013): Assessing causal mechanistic interactions: a peril ratio index of synergy based on multiplicativity. PLoS ONE 8(6):e67424. [SCI]

    62. Lin S-H, Liu C-M, Hwang T-J, Hsieh MH, Hsiao P-C, Faraone SV, Tsuang MT, Hwu H-G, Chen WJ (2013): Performance on the Wisconsin Card Sorting Test in families of schizophrenia patients with different familial loadings. Schizophrenia Bulletin 39: 537-546. [SCI, SSCI]

    63. Lee CS, Liao SF, Liu IC, Lee WC, Cheng ATA (2013): Incidence of first onset alcohol use disorder: a 16-year follow-up in the Taiwanese aborigines. Social Psychiatry and Psychiatric Epidemiology 48(6): 955-963. [SCI]

    64. Tu YK, Chien KL, Chiu YW, Ellison GTH (2013): Seasonal variation in blood pressure is modulated by gender and age but not by BMI in a large Taiwanese population, 1996–2006. Journal of the American Society of Hypertension 7(3): 216-228. [SCI]

    65. Wu HY, Huang JW, Peng YS, Hung KY, Wu KD, Lai MS, Chien KL (2013): Microalbuminuria Screening for Detecting Chronic Kidney Disease in the General Population: A Systematic Review. Renal Failure 35(5): 607-614. [SCI]

    66. Chang KV, Hsiao MY, Chen WS, Wang TG, Chien KL (2013): Effectiveness of intra-articular hyaluronic acid for ankle osteoarthritis treatment- a systematic review and meta-analysis. Archives of Physical Medicine and Rehabilitation 94(5): 951-960. [SCI]

    67. Kuo C-J, Yang S-Y, Liao Y-T, Chen WJ, Lee W-C, Shau W-Y, Chang Y-T, Tsai S-Y, Chen C-C (2013): Second-generation antipsychotic medications and risk of pneumonia in schizophrenia. Schizophrenia Bulletin 39: 648-657. [SCI, SSCI]

    68. Liao H-W, Tsai I-L, Chen G-Y, Kuo C-T, Wei M-F, Hwang T-J, Chen WJ, Shen L-J, Kuo C-H (2013): Simultaneous detection of single nucleotide polymorphisms and copy number variations in the CYP2D6 gene by multiplex polymerase chain reaction combined with capillary electrophoresis. Analytica Chimica Acta 763: 67-75. [SCI]

    69. Chien KL, Lee MS, Tsai YT, Chen PR, Lin HJ, Lee BC, Hsu HC, Lee YT, Chen MF (2013): A Taiwanese food frequency questionnaire correlates with plasma docosahexaenoic acid but not with plasma eicosapentaenoic acid levels. BMC Medical Research Methodology 13(1): 23. [SCI]

    70. Hsieh RL, Lee WC, Lo MT, Liao WC (2013): Postural stability in patients with knee osteoarthritis: comparison with controls and evaluation of relationships between postural stability scores and International Classification of Functioning, Disability and Health Components. Archives of Physical Medicine and Rehabilitation 94: 340-346. [SCI]

    71. Wang S-H, Chen WJ, Chuang L-M, Hsiao P-C, Liu P-H, and Hsiao CK (2013): Inference of cross-level interaction between genes and contextual factors in a matched case-control metabolic syndrome study: a Bayesian approach. PLoS ONE 8: e56693. [SCI]

    72. Lin PY, Chu CY, Chien KL, Lin CP, Tu YK (2013): In-Office Treatment for Dentin Hypersensitivity: A Systematic Review and Network Meta-Analysis. Journal of Clinical Periodontology 40(1): 53-64. [SCI]

    73. Chen YC, Huang YL, Platz EA, Alderete JF, Zheng L, Rider JR, Kraft P, Giovannucci E, Sutcliffe S (2013): Prospective study of effect modification by Toll-like receptor 4 variation on the association between Trichomonas vaginalis serostatus and prostate cancer. Cancer Causes & Control 24(1): 175-180. [SCI]

    74. Hsieh RL, Hsueh YM, Huang HY, Lin MI, Tseng WC, Lee WC (2013): Quality of life and impact of children with unclassified developmental delays. Journal of Paediatrics and Child Health 49: E116-E121. [SCI]

    75. Lien Y-J, Huang S-S, Liu C-M, Hwu H-G, Faraone SV, Tsuang MT, Chen WJ (2013): A genome-wide quantitative linkage scan of niacin skin flush response in families with schizophrenia. Schizophrenia Bulletin 39: 68-76. [SCI, SSCI]

    76. Chen YC, Chen SY, Yip PK, Huang YL, Sun Y, Wen LL, Chu Y-M, Chen TF (2012): Sequence Variants of Toll Like Receptor 4 and late-onset Alzheimer’s disease. PLoS ONE 7(12): e50771. [SCI]

    77. Hsieh RL, Lo MT, Liao WC, Lee WC (2012): Therapeutic effects of short-term monochromatic infrared energy therapy on patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study. Journal of Orthopaedic & Sports Physical Therapy 42(11): 947-956. [SCI]

    78. Kao CF, Jia PL, Zhao, Z, Kuo PH (2012): Enriched pathways for major depressive disorder identified from a genome-wide association study. International Journal of Neuropsychopharmacology 15(10): 1401-1411. [SCI]

    79. Liao Y-T, Chen C-J, Li W-F, Hsu L-I, Tsai L-Y, Huang Y-L, Sun C-W, Chen WJ, Wang S-L (2012): Elevated lactate dehydrogenase activity and increased cardiovascular mortality in the 2 arsenic-endemic areas of southwestern Taiwan. Toxicology and Applied Pharmacology 262: 232-237. [SCI]

    80. Tzeng IS, Lee WC (2012): Detecting differentially expressed genes in heterogeneous diseases using control-only analysis of variance. Annals of Epidemiology 22: 598-602. [SCI]

    81. Chen C-H, Lee YL, Wu M-H, Chen P-J, Wei T-S, Wu C-C, Tung K-Y, Chen WJ (2012): Environmental tobacco smoke and male sex modify the influence of IL-13 genetic variants on cord blood IgE levels. Pediatric Allergy and Immunology 23: 456-463. [SCI]

    82. Hsieh RL, Liao WC, Lee WC (2012): Local and systemic cardiovascular effects from monochromatic infrared therapy in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study. Evidence-based Complementary and Alternative Medicine : 583016. [SCI]

    83. Hsieh RL, Lo MT, Liao WC, Lee WC (2012): Short-term effects of 890-nanometer radiation on pain, physical activity, and postural stability in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study. Archives of Physical Medicine and Rehabilitation 93: 757-64. [SCI]

    84. Liao SF, Lee WC, Chen HC, Chuang LC, Pan MH, Chen CJ (2012): Roles of human papillomavirus infection, high vaginal parity, and their interaction on cervical cancer risks after a follow-up of more than 10 years. Cancer Causes & Control 23: 703-708. [SCI]

    85. Lee WC (2012): Completion potentials of sufficient component causes. Epidemiology 23: 446-453. [SCI]

    86. Chen PC, Chen YC, Lai LC, Tsai MH, Chen SK, Yang PW, Lee YC, Haiso CK, Lee JM, Chuang EY (2012): Use of germline polymorphisms in predicting concurrent chemoradiotherapy response in esophageal cancer. International Journal of Radiation Oncology, Biology, Physics 82(5): 1996-2003. [SCI]

    87. Liao SF, Yang HI, Lee MH, Chen CJ, Lee WC (2012): Fifteen-year population attributable fractions and causal pies of risk factors for newly developed hepatocellular carcinomas in 11,801 men in Taiwan. PLoS ONE 7(4): e34779. [SCI]

    88. Lin WY, Lee WC (2012): Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis. PLoS ONE 7(4): e33716. [SCI]

    89. Lin WY, Lee WC (2012): Presenting uncertainties of odds ratios using empirical-Bayes prediction intervals. PLoS ONE 7: e32022. [SCI]

    90. Chen YY, Liao SF, Ten PR, Tsai CW, Fan HF, Lee WC, Cheng ATA (2012): The impact of media reporting of the suicide of a singer on suicide rates in Taiwan. Social Psychiatry and Psychiatric Epidemiology 47: 215-221. [SCI]

    91. Lin Y-L, Yip P-K, Lai L-C, Chen S-Y, Chen J-H, Yang S-Y, Huang Y-L, Chen T-F, Sun Y, Wen L-L, Chu Y-M, Chen WJ, Chen Y-C (2012): Genetic Polymorphisms of Clusterin (CLU) Gene Are Associated with a Decreased Risk of Alzheimer’s Disease. European Journal of Epidemiology 27: 73-75. [SCI]

    92. Cheng H-C, Sun Y, Lai L-C, Chen S-Y, Lee W-C, Chen J-H, Chen T-F, Chen H-H, Wen L-L, Yip P-K, Chu Y-M, Chen WJ., Chen Y-C (2012): Genetic Polymorphisms of Nerve Growth Factor Receptor (NGFR) and the Risk of Alzheimer’s Disease. Journal of Negative Results in Biomedicine 11: 5.

    93. Kuo C-J, Tsai S-Y, Liao Y-T, Conwell Y, Lee W-C, Huang M-C, Lin S-K, Chen C-C, Chen WJ (2012): Elevated aspartate and alanine aminotransferase levels and natural death among patients with methamphetamine dependence. PLoS ONE 7: e29325. [SCI]

    94. Tu YK, Kraemer N, Lee WC (2012): Addressing the identification problem in age-period-cohort analysis a tutorial on the use of partial least squares and principal components analysis. Epidemiology 23: 583-593. [SCI]

    95. Fu TST, Lee CS, Gunnell D, Lee WC, Cheng ATA (2012): Changing trends in the prevalence of common mental disorders in Taiwan: a 20-year repeated cross-sectional survey. Lancet 381: 235-241. [SCI]

    96. Chen SY, Chen TF, Lai LC, Chen JH, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC (2012): Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease. Journal of Neuroinflammation 9: 21. [SCI]

    97. Hsieh RL, Lin MI, Huang HY, Lee WC (2012): The relationship between the pediatric outcomes data collection instrument and functional impairment in developmentally delayed Chinese children and their parents’ health: implications for child and family-centered medicine. Annals of Human Genetics 1: 574-580. [SCI]

    98. Lin YC, Chang MH, Liao SF, Wu JF, Tiao MM, Lai MW, Lee HC, Lin CC, Wu TC, Lau BH, Tsai TC, Chen HL, Hsu HY, Ni YH, Lee WC, and the Taiwan Infant Stool Color Card Study Group (2011): Decreasing rate of biliary atresia in Taiwan: a survey 2004-2009. Pediatrics 128: E530-E536. [SCI]

    99. Huang Y-H, Lee M-H, Chen WJ, Hsiao CK (2011): Using an uncertainty-coding matrix in Bayesian regression models for haplotype-specific risk detection in family association studies. PLoS ONE 6: e21890. [SCI]

    100. Lin WY, Lee WC (2011): Prioritized subset analysis with floating false discovery rate control: a powerful method to detect differentially expressed genes. Comp Stat Data Analysis 55: 903-913. [SCI]

    101. Lee WC (2011): Bounding the bias of unmeasured factors with confounding and effect-modifying potentials. Statistics in Medicine 30: 1007-1017. [SCI, SSCI]

    102. Chen LH, Lee WC (2011): Two-way minimization: a novel treatment allocation method. PLoS ONE 6: e28604. [SCI]

    103. Tsuang H-C, Liu C-M, Hwang TJ, Hsieh MH, Faraone SV, Tsuang MT, Hwu H-G, Chen WJ (2011): Handedness and schizotypy in nonpsychotic relatives of patients with schizophrenia. Laterality: Asymmetries of Body, Brain and Cognition 16(6): 690-706. [SCI]

    104. Lu, T.P., Lai, L.C., Tsai, M.H., Chen, P.C., Hsu, C.P., Lee, J.M., Hsiao, C.K., Chuang, E.Y. (2011): Integrated Analyses of Copy Number Variations and Gene Expression in Lung Adenocarcinoma. PLoS ONE 6(9): e24829. [SCI]

    105. Liu IC, Liao SF, Lee WC, Kao CY, Jenkins R, Cheng ATA 2011): A cross-ethnic comparison on incidence of suicide. Psychological Medicine 41: 1213-21. [SCI, SSCI]

    106. Lien Y-J, Hsiao P-C, Liu C-M, Faraone SV, Tsuang MT, Hwu H-G, Chen WJ (2011): A genome-wide linkage scan for distinct subsets of schizophrenia characterized by age at onset and neurocognitive deficits. PLoS ONE 6(8): e24013. [SCI]

    107. Lee, M.H., Tzeng, J.Y., Huang, S.Y., and Hsiao, C.K. (2011): Combining an evolution-guided clustering algorithm and haplotype-based LRT in family association studies. BMC Genetics 12: 48. [SCI]

    108. Liu C-M, Fann CS-J, Chen C-Y, Liu Y-L, Oyang Y-J, Yang W-C, Chang CC, Wen C-C, Chen WJ, Hwang TJ, Hsieh MH, Liu C-C, Faraone SV, Tsuang MT, Hwu H-G (2011): ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function. Biological Psychiatry 70: 51-58. [SCI]

    109. Lai C-Y, Yu S-L, Hsieh MH, Chen C-H, Chen H-Y, Wen C-C, Huang Y-H, Hsiao P-C, Hsiao CK, Liu C-M, Yang P-C, Hwu H-G, Chen WJ (2011): MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia. PLoS ONE 6: e21635. [SCI]

    110. Huang HH, Shih WL, Li YH, Wu CF, Chen PJ, Lin CL, Liu CJ, Liaw YF, Lin SM, Lee SD, Yu MW (2011): Hepatitis B viremia: its heritability and association with common genetic variation in the interferon-γ signaling pathway. Gut 60: 99-107. [SCI]

    111. Wang S-H, Hsiao P-C, Hsiao CK, Liu P-H, Chien K-L, Lin S-R, Lee W-C, Chen WJ (2011): Multilevel analysis of habitual physical activity and metabolic syndrome in northern Taiwan. Preventive Medicine 53: 34-38. [SCI]

    112. Huang HY, Lee WC (2011): A triple combination strategy corrected population stratification bias and saved genotyping cost. Journal of Clinical Epidemiology 64: 517-524. [SCI]

    113. Lin K-P, Chen S-Y, Lai L-C, Huang Y-L, Chen T-F, Chen J-H, Sun Y, Wen L-L, Yip P-K, Chu Y-M, Chen WJ, Chen Y-C (2011): Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer’s disease. PLoS ONE 6(6): e20573. [SCI]
      (Outstanding Master Thesis Award, Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2011 Joint Annual Meeting and Symposium)

    114. Liu C-C, Lai M-C, Liu C-M, Chiu Y-N, Hsieh MH, Hwang T-J, Chien Y-L, Chen WJ, Hua M-S, Hsiung P-C, Huang Y-C, Hwu H-G (2011): Follow-up of subjects with suspected pre-psychotic state in Taiwan. Schizophrenia Research 126: 65-70. [SCI, SSCI]

    115. Kao C-F, Fang Y-S, Zhao Z-M, Kuo P-H (2011): Prioritization and evaluation of depression candidate genes by combining multidimensional data resources. PLoS ONE 6(4): e18696. [SCI]

    116. Lien WC, Lee WC, Wang HP, Chen YC, Liu KL, Chen CJ (2011): Male gender is a risk factor for recurrent appendicitis following nonoperative treatment. World Journal of Surgery 35: 1636-42. [SCI]

    117. Tsai M-Y, Hsiao CK, Chen WJ (2011): Extended Bayesian model averaging for gene-gene and gene-environment interactions in GLMMs with a schizophrenia family study. Annals of Human Genetics 75: 62-77. [SCI]

    118. Demaria S, Pikarsky E, Karin M, Coussens L M, Chen Y-C, El-Omar E M, Trinchieri G, Dubinett S M, Mao J T, Szabo E, Krieg A, Weiner G, Fox B A, Coukos G, Wang E, Abraham R T, Carbone M, and Lotze M T (2010): Cancer and inflammation: promise for biological therapy. Journal of Immunotherapy 33(4): 335-351. [SCI]

    119. Chen Y-C, Chen T-F, Yip P-K, Hu C-Y, Chu Y-M, Chen J-H (2010): Body mass index at early age and the risk of dementia. Archives of Gerontology and Geriatrics 50 (Supplement 1): S48-S52. [SCI]

    120. Chen Y-C, Su H-JJ, Hsueh Y-M, Smith T J, Ryan L M, Chao S-C, Lee JY-Y, Christiani D C, Guo Y-LL (2010): Early-life or lifetime sun exposure, sun reaction, and the risk of squamous cell carcinoma in an Asian population. Cancer Causes and Control 21(5): 771-776. [SCI]

    121. Yu H-H, Liu P-H, Lin Y-C, Chen WJ, Lee J-H, Wang L-C, Yang Y-H, Chiang B-L (2010): Interleukin-4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients. Lupus 19 : 1219-1228. [SCI]

    122. Lien Y-J, Liu C-M, Faraone SV, Tsuang MT, Hwu H-G, Hsiao P-C, Chen WJ (2010): A genome-wide quantitative trait loci scan of neurocognitive performances in schizophrenia families. Genes, Brain and Behavior: 9: 695-702. [SCI]

    123. Chien K-L, Wang K-C, Chen Y-C, Chao C-L, Hsu H-C, Chen M-F, Chen WJ (2010): Common sequence variant in pharmacodynamic and pharmacokinetic pathway-related genes conferring low density lipoprotein cholesterol response to statins. Pharmacogenomics 11: 309-317. [SCI]

    124. Liu Yu-Li, Liu Chih-Min, Fann Cathy Shen-Jang, Yang Wei Chih, Chen Ya-Hui, Tseng Li-Jung, Liu Shih-Kai, Hsieh Ming H., Hwang Tzung-Jeng, Chan Hung-Yu, Chen Jiann-Jyh, Chen Wei J., and Hwu Hai-Gwo (2010): Genetic variants of IL-6 and its receptor are not associated with schizophrenia in Taiwan. Neuroscience Letters 468: 330-333. [SCI]

    125. Lien Y-J, Tsuang H-C, Chiang A, Liu C-M, Hsieh M-H, Hwang T-J, Liu SK, Hsiao P-C, Faraone SV, Tsuang MT, Hwu H-G, Chen WJ. (2010): The multidimensionality of schizotypy in nonpsychotic relatives of patients with schizophrenia and its applications in ordered subsets linkage analysis of schizophrenia. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 153B: 1-9. [SCI]

    126. Lee CH, Liu CM, Wen CC, Chang SM, Hwu HG (2010): Genetic copy number variants in sib pairs both affected with schizophrenia. Journal of Biomedical Science 17: 2. [SCI]

    127. Chou L-N, Kuo P-H, Lin CCH, Chen WJ (2010): Genetic and environmental influences on the Wisconsin Card Sorting Test performance in healthy adolescents: a twin/sibling study. Behavior Genetics 40: 22-30. [SCI]

    128. Chien KL, Hsu HC, Chen YC, Su TC, Lee YT, Chen MF (2009): Association between sequence variant of c.553G>T in the apolipoprotein A5 gene and metabolic syndrome, insulin resistance and carotid atherosclerosis. Translational Research 154(3): 133-141. [SCI]

    129. Lin S-H, Liu CM, Liu YL, Fann CSJ, Hsiao PC, Wu JY, Hung SI, Chen CH, Wu HM, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Chang CC, Yang WC, Lin JJ, Chou FHC, Faraone SV, Tsuang MT, Hwu HG, Chen WJ (2009): Clustering by neurocognition for fine-mapping of the schizophrenia susceptibility loci on chromosome 6p. Genes, Brain and Behavior 8: 785-794. [SCI]

    130. Pan Y-J, Chen S-H, Chen WJ, Liu S-K (2009): Affect recognition as an independent social function determinant in schizophrenia. Comprehensive Psychiatry 50: 443-452. [SCI, SSCI]

    131. Huang G-H, Hsieh C-C, Chen C-H, Chen WJ (2009): Statistical validation of endophenotypes using a surrogate endpoint analytic analogue. Genetic Epidemiology 33: 549-558. [SCI]

    132. Chen P-C, Huang S-Y, Chen WJ, Hsiao CK (2009): A new regularized least squares support vector regression for gene selection. BMC Bioinformatics 10: 44. (highly accessed). [SCI]

    133. Chien, KL, Lin, YL, Wen, HC, Lin, HP, Yen, CT, Lin SW, Kao JT (2009): Common sequence variant in lipoprotein lipase gene conferring triglyceride response to fibrate treatment. Pharmacogenomics 10(2): 267-276. [SCI]

    134. Liu P-H, Chang Y-C, Jiang Y-D, Chen WJ, Chang T-J, Kuo S-S, Lee K-C, Hsiao P-C, Chiu KC, Chuang L-M (2009): Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults. Journal of Clinical Endocrinology & Metabolism 94: 3575-3582. [SCI]

    135. Liao S-Y, Lin S-H, Liu C-M, Hsieh MH, Hwang TJ, Liu SK, Guo S-C, Hwu H-G, Chen WJ (2009): Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia. Genes, Brain and Behavior 8: 228-237. [SCI]

    136. Chang S-S, Liu C-M, Lin S-H, Hwu H-G, Hwang T-J, Liu SK, Hsieh M-H, Guo S-C, Chen WJ (2009): Impaired flush response to niacin skin patch among schizophrenia patients and their nonpsychotic relatives: the effect of genetic loading. Schizophrenia Bulletin 35: 213-221. [SCI, SSCI]

    137. Liu P-H#, Jiang Y-D#, Chen WJ#, Chang C-C, Lee T-C, Sun HS, Chuang L-M (contributed equally) (2008): Genetic and environmental influences on levels of adiponectin, leptin, and BMI among adolescents in Taiwan: a multivariate twin/sibling analysis. Twin Research and Human Genetics 11: 495-504. [SCI]

    138. Chien, Kuo-Liong, Liau, Chiau-Suong, Chen, Ming-Fong, Lee, Yuan-Teh, Jeng, Jiann-Shing, Hwang, Bao-Show and Su, Ta-Chen (2008): Primary Hypercholesterolemia, Carotid Atherosclerosis and Insulin Resistance Among Chinese. Lipids 43(2): 117-124. [SCI]

    139. Liu, Y.-L., Fann, C.S.-J., Liu, C.-M., Chen, W.J., Wu, J.-Y., Hung, S.-I., Chen, C.-H., Jou, Y.-S., Liu, S.-K., Hwang, T.-J., Hsieh, M.H., Chang, C.C., Yang, W.-C., Lin, J.-J., Chou, F.H.-C., Faraone, S.V., Tsuang, M.T., Hwu, H.-G. (2008): RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function. Biological Psychiatry 64: 789-796. [SCI]

    140. Jeng S-F, Hsu C-H, Tsao P-N, Chen P-S, Chou H-C, Kao H-A, Hsieh W-S (2008): Bronchopulmonary dysplasia predicts adverse developmental and clinical outcomes in very low birth weight infants throughout infancy. Developmental Medicine & Child Neurology 50(1): 51-57. [SCI]

    141. Chien, Kuo-Liong, Fang, Woei-Horng, Wen, Hui-Chin, Lin, Hsing-Pei, Lin, Yen-Lin, Lin, Shu-Wha, Wu, June-Hsieh and Kao, Jau-Tsuen (2008): APOA1/C3/A5 haplotype and risk of hypertriglyceridemia in Taiwanese. Clinica Chimica Acta 390(1-2): 56-62. [SCI]

    142. Chien, Kuo-Liong, Chen, Ming-Fong, Hsu, Hsiu-Ching, Su, Ta-Chen, Chang, Wei-Tien, Lee, Chii-Ming and Lee, Yuan-Teh (2008): Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population. Clinica Chimica Acta 388(1-2): 78-83. [SCI]

    143. Yu S-L, Chen H-Y, Chang G-C, Chen C-Y, Chen H-W, Singh S, Cheng C-L, Yu C-J, Lee Y-C, Chen H-S, Su T-J, Chiang C-C, Li H-N, Hong Q-S, Su H-Y, Chen C-C, Chen W-J, Liu C-C, Chan W-K, Chen WJ, Li K-C, Chen JJW, Yang P-C (2008): MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 13: 48-57. [SCI]

    144. Liu Y-L, Fann CS-J, Liu C-M, Chang CC, Yang WC, Wu J-Y, Hung S-I, Chan H-Y, Chen J-J, Hsieh MH, Hwang T-J, Faraone SV, Tsuang MT, Chen WJ, Hwu H-G (2007): HTF9C gene of 22q11.21 region associates with schizophrenia having deficit sustained attention. Psychiatric Genetics 17: 333-338. [SCI]

    145. Liu YL, Fann CS, Liu CM, Chang CC, Yang WC, Hung SI, Yu SL, Hwang TJ, Hsieh MH, Liu CC, Tsuang MM, Wu JY, Jou YS, Faraone SV, Tsuang MT, Chen WJ, Hwu HG (2007): More evidence supportsthe association of PPP3CC with schizophrenia. Molecular Psychiatry 12: 966-74. [SCI]

    146. Liu CM, Liu YL, Fann CS, Yang WC, Wu JY, Hung SI, Chen WJ, Chueh CM, Liu WM, Liu CC, Hsieh MH, Hwang TJ, Faraone SV, Tsuang MT, Hwu HG (2007): No association evidence between schizophrenia and dystrobrevin-binding protein 1 (DTNBP1) in Taiwanese families. Schizophrenia Research 93: 391-398. [SCI, SSCI]

    147. Liu CM, Liu YL, Fann CS, Chen WJ, Yang WC, Ouyang WC, Chen CY, Jou YS, Hsieh MH, Liu SK, Hwang TJ, Faraone SV, Tsuang MT, Hwu HG (2007): Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families. Genes, Brain and Behavior 6: 497-502. [SCI]

    148. Lin, S.-H., Liu, C.-M., Chang, S.-S., Hwu, H.-G., Liu, S. K., Hwang, T. J., Hsieh, M.-H., Guo, S.-C. & Chen, W.J. (2007): Familial aggregation in skin flush response to niacin patch among schizophrenic patients and their nonpsychotic relatives. Schizophrenia Bulletin 33: 174-182. [SCI, SSCI]

    149. Chen,H.-Y., Yu, S.-L., Chen, C.-H., Chang, G.-C., Chen, C.-Y., Chen,W.J., Chen, J.J.W., Yang, P.-C. (contributed equally) (2007): A five-gene signature and clinical outcome in non-small-cell lung cancer. New England Journal of Medicine 356: 11-20. [SCI]

    150. Liu YL, Fann CS, Liu CM, Chen WJ, Wu JY, Hung SI, Chen CH, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Ouyang WC, Chan HY, Chen JJ, Yang WC, Lin CY, Lee SF, Hwu HG (2006): A single nucleotide polymorphism fine mapping study of chromosome 1q42.1 reveals the vulnerability genes for schizophrenia, GNPAT and DISC1: Association with impairment of sustained attention. Biological Psychiatry 60(6): 554-62. [SCI]

    151. Liu YL, Fann CS, Liu CM, Chang CC, Wu JY, Hung SI, Liu SK, Hsieh MH, Hwang TJ, Chan HY, Chen JJ, Faraone SV, Tsuang MT, Chen WJ, Hwu HG (2006): No association of G72 and D-amino acid oxidase genes with schizophrenia. Schizophrenia Research 87(1-3): 15-20. [SCI, SSCI]

    152. Faraone SV, Hwu HG, Liu CM, Chen WJ, Tsuang MM, Liu SK, Shieh MH, Hwang TJ, OuYang WC, Chen CY, Chen CC, Lin JJ, Chou FHC, Chueh CM, Liu WM, Hall MH, Su J, Van Eerdewegh P, and Tsuang MT (2006): Genome scan of Han Chinese schizophrenia families from Taiwan: Confirmation of linkage to 10q22.3. American Journal of Psychiatry 163:1760–1766. [SCI, SSCI]

    153. Liu YL, Fann CSJ, Liu CM, Pan CC, Wu JY, Hung SI, Chan HY, Chen JJ, Liu SK, Shieh MH, Hwang TJ, OuYang WC, Chen CY, Lin JJ, Chou FHC, Chueh CM, Liu WM, Tsuang MM, Faraone SV, Tsuang MT, Chen WJ, Hwu HG (2006): Evaluation of RGS4 as a candidate gene for schizophrenia. American Journal of Medical Genetics (Neuropsychiatric Genetics) 141: 418-420. [SCI]

    154. Liu YL, Fann CSJ, Liu CM, Pan CC, Wu JY, Hung SI, Chan HY, Chen JJ, Liu SK, Shieh MH, Hwang TJ, OuYang WC, Chen CY, Lin JJ, Chou FHC, Chueh CM, Liu WM, Tsuang MM, Faraone SV, Tsuang MT, Chen WJ, Hwu HG (2006): Absence of significant associations between four AKT1 SNP markers and schizophrenia in Taiwanese. Psychiatric Genetics 16: 39-41. [SCI]

    155. Kuo S-Y, Liu P-H, Chuang L-M, Chen WJ (2006): The Taipei Adolescent Twin/Sibling Family Study II: Depression, insulin resistance, and hormonal factors. Twin Research and Human Genetics 9: 895-898. [SCI]

    156. Tsai, M-F, Wang, C-C, Chang, G-C, Chen, C-Y, Chen, H-Y, Cheng, C-L, Yang, Y-P, Wu, C-Y, Shih, F-Y, Liu, C-C, Lin, H-P, Jou, Y-S, Lin, S-C, Lin, C-W, Chen, WJ, Chan, W-K, Chen, JJW, Yang, P-C (2006): A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non–small-cell lung carcinoma. Journal of the National Cancer Institute 98: 825-838. [SCI]

    157. Chen CC, Yang SY, Liu CJ, Lin CL, Liaw YF, Lin SM, Lee SD, Chen PJ, Chen CJ, Yu MW (2005): Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma. International Journal of Epidemiology 34: 1310-1318. [SCI]

    158. Lin HF, Liu Y-L, Liu C-M, Hung S-I, Hwu H-G, Chen WJ (2005): Neuregulin 1 gene and variations in perceptual aberration of schizotypal personality in adolescents. Psychological Medicine 35: 1589-1598. [SCI]

    159. Wu, Shyh-Jong, Chiang, Fu-Tien, Chen, W.J., Liu, Pi-Hua, Hsu, Kwan-Lih,Hwang, Juey-Jen, Lai, Ling-Ping, Lin, Jiunn-Lee, Tseng, Chuen-Den, Tseng, Yung-Zu (2004): Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype versus haplotype analysis. Physiological Genomics 17: 79-86. [SCI]

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